BRCC45 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-BRCC45 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | BRCC45 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | BRCC45 was initially suggested to be a housekeeping protein that is highly expressed in brain and reproductive organs. Later experiments indicated BRCC45 forms a complex with the breast and ovarian predisposition proteins BRCA1 and BRCA2 as well as RAD51 and BRCC36. This complex has a ubiquitin E3 ligase activity and is thought to enhance cellular survival following DNA damage. BRCC45 has also been suggested to function as a death receptor-associated anti-apoptotic protein by inhibiting the BID-induced activation of the mitochondrial apoptotic pathway. Higher levels of BRCC45 were detected in the majority of hepatocellular carcinomas, suggesting that BRCC45 may promote tumorigenesis when overexpressed. At least three isoforms of BRCC45 are |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 18 amino acid peptide from near the amino terminus of human BRCC45. |
| Other Names | [BRCA1, BRCA2-containing complex subunit 45, Brain and reproductive organ expressed, BRE, TNFRSF1A modulator] |
| Gene, Accession # | [BRCC45], Gene ID: 9577, NCBI: NP_004890 |
| Catalog # | MBS9403407 |
| Price | $320 |
| Order / More Info | BRCC45 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies