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Antigenic Specificity | Phospho-ABL1/2 -Y393/429 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks. |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Y393/429 of human ABL1/2 Calculated Molecular Weight: 210kDa |
Other Names | [Phospho-ABL1; ABL2-Y393; 429: ABL; JTK7; p150; c-ABL; v-abl; bcr/abl/ ARG; ABLL], [ABL1; ABL1; ABL; JTK7; p150; c-ABL; v-abl; c-ABL1; bcr/abl; ABL; JTK7] |
Gene, Accession # | [ABL1/ABL2], Gene ID: 25, NCBI: P00519.4, UniProt: P00519 |
Catalog # | MBS128381 |
Price | $235, $350, $525 |
Order / More Info | Phospho-ABL1/2 -Y393/429 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |