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Antigenic Specificity | Phospho-Cofilin (Ser3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB); Immunohistochemistry (IHC); ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect endogenous levels of Cofilin (Ser3) in human; mouse and rat samples. Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane; increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration. |
Immunogen | Immunogen: Synthesized peptide derived from human Cofilin around the phosphorylation site of S3 |
Other Names | [Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform; CFL1; CFL], [CFL1; CFL; p18] |
Gene, Accession # | [CFL1], Gene ID: 3716, NCBI: NP_005498.1, UniProt: P23528 |
Catalog # | MBS846145 |
Price | $335 |
Order / More Info | Phospho-Cofilin (Ser3) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |