MCK10/NEP/DDR1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMCK10/NEP/DDR1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, Flow Cytometry (FC/FACS), Direct ELISA (EIA)
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DescriptionSpecificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for MCK10/NEP/DDR1 detection. Tested with WB, IHC-P, FCM, Direct ELISA in Human; Mouse; Rat.Background: DDR1(Discoidin domain receptor family, member 1) also known as NEP, EDDR1, NTRK4, TRKE, DDR, CAK or RTK6, is a human gene. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen.This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain.The DDR1 gene is mapped on 6p21.33. The fibrillar collagens and immobilized collagen activa
ImmunogenImmunogen: E. coli-derived human MCK10/NEP/DDR1 recombinant protein (Position: R341-A909).
Other Names[Epithelial discoidin domain-containing receptor 1; Epithelial discoidin domain receptor 1; CD167 antigen-like family member A; Cell adhesion kinase; Discoidin receptor tyrosine kinase; HGK2; Mammary carcinoma kinase 10; MCK-10; Protein-tyrosine kinase 3A; Protein-tyrosine kinase RTK-6; TRK E; Tyrosine kinase DDR; Tyrosine-protein kinase CAK; CD167a; DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE]
Gene, Accession #[DDR1], Gene ID: 780, NCBI: NP_001189450.1, UniProt: Q08345
Catalog #MBS1752844
Price$315
Order / More InfoMCK10/NEP/DDR1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Bhatt, R. S., Tomoda, T., Fang, Y., Hatten, M. E.Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons. Genes Dev. 14: 2216-2228, 2000. 2. Edelhoff, S., Sweetser, D. A., Disteche, C. M. Mapping of the NEP receptor tyrosine kinase gene to human chromosome 6p21.3 and mouse chromosome 17C. Genomics 25: 309-311, 1995. 3. Hou, G., Vogel, W., Bendeck, M. P. The discoidin domain receptor tyrosine kinase DDR1 in arterial wound repair. J. Clin. Invest. 107: 727-735, 2001.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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