Phospho-AhR (Ser36) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-AhR (Ser36)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: Phospho-AhR (Ser36) antibody detects endogenous levels of AhR only when phosphorylated at Serine 36. Description: The Aryl Hydrocarbon Receptor (AHR), also known as the dioxin receptor, is a ligand-activated helix/loop/helix transcription factor found in a variety of vertebrate species. The known ligands for AHR are foreign planar aromatic compounds, such as polycyclic aromatic compounds and halogenated aromatic compounds such as 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD).Function: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemic
ImmunogenImmunogen: A synthesized peptide derived from human AhR around the phosphorylation site of Serine 36 Subcellular Location: Cytoplasm. Nucleus. Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. Tissue Specificity: Expressed in all tissues tested including blood, brain, heart, kidney, liver, lung, pancreas and skeletal muscle. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100
Other Names[Ah receptor; AhR; AHR_HUMAN; Aromatic hydrocarbon receptor; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor precursor; bHLHe76; Class E basic helix loop helix protein 76; Class E basic helix-loop-helix protein 76; HGNC:348; AHH; AhR repressor; AhRR; AHRR_HUMAN; aryl hydrocarbon hydroxylase regulator; aryl hydrocarbon receptor regulator; Aryl hydrocarbon receptor repressor; Arylhydrocarbon receptor repressor; bHLHe77; Class E basic helix-loop-helix protein 77; Dioxin receptor repressor; KIAA1234; MGC167813; MGC176630; OTTHUMP00000221488; OTTHUMP00000221489]
Gene, Accession #[AhR], Gene ID: 196, NCBI: NP_001612.1, UniProt: P35869
Catalog #MBS9601049
Price$240, $280
Order / More InfoPhospho-AhR (Ser36) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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