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Antigenic Specificity | MICA |
Clone | [6D4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a kappa |
Format | affinity purified |
Size | 0.025 mg, 0.1 mg |
Concentration | 500 ug/ml |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The 6D4 monoclonal antibody reacts with the human major histocompatibility complex class I chain-related, MICA and MICB proteins. MICA and MICB are related proteins of 83% amino acid similarity, and show homology with classical human leukocyte antigen molecules. The structure of MICA and MICB are similar to classical HLA class I chains, however they do not bind beta2 microglobulin or bind peptide typical of HLA class I. MICA and MICB are expressed on the cell surface of endothelial cells, fibroblasts, gastric epithelium and PHA-stimulated T cells, and act as a ligand for NKGD2 expressed on the surface of NK cells, gamma delta T cells and alphabeta CD8+ T cells. There is evidence to suggest that human cytomegalovirus subverts NK cell detecti |
Immunogen | n/a |
Other Names | [Mouse MICA; MICA; MICA; MICA; MICB; MICA; MICA/MICB; MICA/MICB; MICA; MICB; MICA] |
Gene, Accession # | [MICA], Gene ID: 100507436, NCBI: CAA77031.1, UniProt: Q29983 |
Catalog # | MBS5309279 |
Price | $180, $240 |
Order / More Info | MICA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |