MICA Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMICA
Clone[6D4]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a kappa
Formataffinity purified
Size0.025 mg, 0.1 mg
Concentration500 ug/ml
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionThe 6D4 monoclonal antibody reacts with the human major histocompatibility complex class I chain-related, MICA and MICB proteins. MICA and MICB are related proteins of 83% amino acid similarity, and show homology with classical human leukocyte antigen molecules. The structure of MICA and MICB are similar to classical HLA class I chains, however they do not bind beta2 microglobulin or bind peptide typical of HLA class I. MICA and MICB are expressed on the cell surface of endothelial cells, fibroblasts, gastric epithelium and PHA-stimulated T cells, and act as a ligand for NKGD2 expressed on the surface of NK cells, gamma delta T cells and alphabeta CD8+ T cells. There is evidence to suggest that human cytomegalovirus subverts NK cell detecti
Immunogenn/a
Other Names[Mouse MICA; MICA; MICA; MICA; MICB; MICA; MICA/MICB; MICA/MICB; MICA; MICB; MICA]
Gene, Accession #[MICA], Gene ID: 100507436, NCBI: CAA77031.1, UniProt: Q29983
Catalog #MBS5309279
Price$180, $240
Order / More InfoMICA Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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