DRD4 (Center), 365-391 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDRD4 (Center), 365-391
Clone[625CT1.5.4]
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1
Formatunconjugated
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.3
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis DRD4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from the Central region of human DRD4. This gene encodes the D4 subtype of the dopamine receptor.The D4 subtype is a G-protein coupled receptor which inhibitsadenylyl cyclase. It is a target for drugs which treatschizophrenia and Parkinson disease. Mutations in this gene havebeen associated with various behavioral phenotypes, includingautonomic nervous system dysfunction, attentiondeficit/hyperactivity disorder, and the personality trait ofnovelty seeking. This gene contains a polymorphic number (2-10copies) of tandem 48 nt repeats; the sequence shown contains fourrepeats.
Immunogenn/a
Other Names[D(4) dopamine receptor; D(2C) dopamine receptor; Dopamine D4 receptor; DRD4]
Gene, Accession #[DRD4], Gene ID: 1815, NCBI: NP_000788.2, UniProt: P21917
Catalog #MBS9200009
Price$165, $370
Order / More InfoDRD4 (Center), 365-391 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLai, J.H., et al. Brain Res. 1359, 227-232 (2010) : Paloyelis, Y., et al. Neuropsychopharmacology 35(12):2414-2426(2010) Gadow, K.D., et al. Eur. J. Neurosci. 32(6):1058-1065(2010) Szekely, A., et al. Genes Brain Behav. (2010) In press : Chio, C.L., et al. J. Biol. Chem. 269(16):11813-11819(1994)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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