BAD (Phospho-Ser112) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | BAD (Phospho-Ser112) |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Immunoblotting (IB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects endogenous human and mouse BAD only when phosphorylated at serine 112. The protein encoded by the BAD gene is a member of the Bcl-2 family whose members are regulators of programmed cell death. BAD protein positively regulates cell apoptosis by forming heterodimers with Bcl-xL and Bcl-2 and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin, were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. |
| Immunogen | Antigen: Peptide sequence that includes phosphorylation site of serine 112 (H-S-S(p)-Y-P) derived from mouse BAD and conjugated to KLH. |
| Other Names | [bcl2-associated agonist of cell death isoform 1; Bcl2-associated agonist of cell death; bcl2-associated agonist of cell death; BCL2-associated agonist of cell death; Bcl-2-binding component 6; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell death], [Bad; Bad; Bbc2; AI325008; Bbc6; BAD] |
| Gene, Accession # | [BAD], Gene ID: 12015, NCBI: NP_031548.1, UniProt: Q61337 |
| Catalog # | MBS191078 |
| Price | $340 |
| Order / More Info | BAD (Phospho-Ser112) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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