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Antigenic Specificity | IL-12Rbeta1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IL-12Rbeta1 Polyclonal Antibody detects endogenous levels of IL-12Rbeta1 protein. The interleukin 12 receptor subunit beta 1 encoded by IL12RB1 is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibil |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human IL-12Rbeta1 |
Other Names | [Rabbit IL-12Rbeta1; IL12RB1; IL12R; IL12RB; Interleukin-12 receptor subunit beta-1; IL-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12R-beta-1; IL-12RB1; IL-12 receptor beta component; CD212] |
Gene, Accession # | [IL-12Rbeta1], Gene ID: 3594, NCBI: NP_001276952.1, UniProt: P42701 |
Catalog # | MBS9703989 |
Price | $130, $220, $325 |
Order / More Info | IL-12Rbeta1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |