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Antigenic Specificity | SIGLEC12 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against SIGLEC12. It was validated on Western Blot using a cell lysate as a positive control.Target Description: Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. SIGLEC12 is a member of the SIGLEC3-like subfamily of SIGLECs. SIGLEC12, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage s |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SIGLEC12 |
Other Names | [sialic acid-binding Ig-like lectin 12 isoform a; Sialic acid-binding Ig-like lectin 12; Sialic acid-binding Ig-like lectin-like 1] |
Gene, Accession # | [SIGLEC12], Gene ID: 89858, NCBI: NP_443729, UniProt: Q96PQ1 |
Catalog # | MBS3209850 |
Price | $335 |
Order / More Info | SIGLEC12 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |