ADAM30 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ADAM30 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ADAM30 antibody detects endogenous levels of total ADAM30. Function: Plays a role in lysosomal amyloid precursor protein (APP) processing by cleaving and activating CTSD/cathepsin D which leads to APP degradation (PubMed:27333034).Subunit Structure: Interacts with CTSD; this leads to activation of CTSD.Similarity: The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme. |
| Immunogen | Immunogen: A synthesized peptide derived from human ADAM30 Subcellular Location: Membrane. Tissue Specificity: Expressed in brain neurons (at protein level) (PubMed:27333034). Expressed in testis (PubMed:10512762). Predicted Cross Reactivity: Pig, Rabbit Similarity: Pig (88%), Rabbit (88%) |
| Other Names | [A disintegrin and metallopeptidase domain 30; ADA30_HUMAN; ADAM 30; ADAM metallopeptidase domain 30; ADAM30; Disintegrin and metalloproteinase domain-containing protein 30; EC 3.4.24.-; MGC132801; MGC132802; OTTHUMP00000014034; Svph4] |
| Gene, Accession # | [ADAM30], Gene ID: 11085, NCBI: NP_068566.2, UniProt: Q9UKF2 |
| Catalog # | MBS9609482 |
| Price | $240, $280 |
| Order / More Info | ADAM30 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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