MDC1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MDC1 |
| Clone | [P2B11] |
| Host Species | Mouse |
| Reactive Species | mouse, human, chimpanzee, bovine |
| Isotype | IgG1 |
| Format | peroxidase (HRP) conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Immunofluorescence (IF), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects ~184kDa. This antibody recognizes MDC1 at or around the N-terminus Scientific Background: MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139. |
| Immunogen | n/a |
| Other Names | [Nuclear factor with BRCT domains1; mediator of DNA damage checkpoint 1], [Mdc1; Mdc1; Nfbd1; AA413496; mKIAA0170; 6820401C03; Kiaa0170] |
| Gene, Accession # | Gene ID: 240087, NCBI: NP_001010833.2, UniProt: Q5PSV9 |
| Catalog # | MBS800223 |
| Price | $405 |
| Order / More Info | MDC1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Lou Z., et al. (2004) J Biol Chem. 279(45): 46359-46362. 2. Luo K., Yuan J, Lou Z. (2011) J Biol Chem. 286(32): 28192-28199. 3. Strauss C., Halevy T., Macarov M., Argaman L., and Goldbery M. (2011) DNA Repair (Amst.). 10(8): 806-814. 4. Wilson K.A., et al. (2011) Mol Cancer Res. 9(6): 766-781. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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