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Antigenic Specificity | AQP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AQP4 antibody detects endogenous levels of total AQP4. Description: Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.Subunit Structure: Homotetramer. Part of a complex containing MLC1, TRPV4, HEPACAM and ATP1B1.Post-translational Modifications: Phosphorylation by PKC at Ser-180 reduces conductance by 50%. Phosphorylation by PKG at Ser-111 in response to glutamats increases conductance by 40% (By similarity).Similarity: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA). Belongs to the MIP/aquaporin (TC 1.A.8) family. |
Immunogen | Immunogen: A synthesized peptide derived from human AQP4 Subcellular Location: Membrane. Tissue Specificity: Brain-muscle > > heart, kidney, lung, and trachea. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog, Chicken Similarity: Pig (90%), Bovine (90%), Horse (90%), Rabbit (90%), Dog (80%), Chicken (80%) |
Other Names | [AQP 4; AQP-4; AQP4; AQP4_HUMAN; Aquaporin type 4; Aquaporin-4; Aquaporin4; HMIWC 2; HMIWC2; Mercurial insensitive water channel; Mercurial-insensitive water channel; MGC22454; MIWC; WCH 4; WCH4] |
Gene, Accession # | [AQP4], Gene ID: 361, NCBI: NP_001641.1, UniProt: P55087 |
Catalog # | MBS9601337 |
Price | $240, $280 |
Order / More Info | AQP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |