AQP4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAQP4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: AQP4 antibody detects endogenous levels of total AQP4. Description: Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.Subunit Structure: Homotetramer. Part of a complex containing MLC1, TRPV4, HEPACAM and ATP1B1.Post-translational Modifications: Phosphorylation by PKC at Ser-180 reduces conductance by 50%. Phosphorylation by PKG at Ser-111 in response to glutamats increases conductance by 40% (By similarity).Similarity: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA). Belongs to the MIP/aquaporin (TC 1.A.8) family.
ImmunogenImmunogen: A synthesized peptide derived from human AQP4 Subcellular Location: Membrane. Tissue Specificity: Brain-muscle > > heart, kidney, lung, and trachea. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog, Chicken Similarity: Pig (90%), Bovine (90%), Horse (90%), Rabbit (90%), Dog (80%), Chicken (80%)
Other Names[AQP 4; AQP-4; AQP4; AQP4_HUMAN; Aquaporin type 4; Aquaporin-4; Aquaporin4; HMIWC 2; HMIWC2; Mercurial insensitive water channel; Mercurial-insensitive water channel; MGC22454; MIWC; WCH 4; WCH4]
Gene, Accession #[AQP4], Gene ID: 361, NCBI: NP_001641.1, UniProt: P55087
Catalog #MBS9601337
Price$240, $280
Order / More InfoAQP4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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