Edit |   |
---|---|
Antigenic Specificity | MEK4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Dual specificity mitogen-activated protein kinase kinase 4(MAP2K4) detection. Tested with WB in Human, Mouse, Rat. Background: Dual specificity mitogen-activated protein kinase kinase 4(MAP2K4), also called SEK1 or JNKK1, is an enzyme that in humans is encoded by the MAP2K4 gene. It is mapped to 17p12. This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK1. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. MAP2K4 w |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MEK4 (360-378aa ELLKHPFILMYEERAVEVA), different from the related mouse and rat sequences by one amino acid. |
Other Names | [Dual specificity mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4; c Jun N terminal kinase kinase 1; C-JUN N-terminal kinase kinase 1; Dual specificity mitogen activated protein kinase kinase 4; Dual specificity mitogen-activated protein kinase kinase 4; JNK Activated Kinase 1; JNK activating kinase 1; JNK-activating kinase 1; JNKK; JNKK1; MAP kinase kinase 4; Map2k4; MAPK ERK kinase 4; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; MEK 4; MEK4; Mitogen activated protein kinase kinase 4; MKK 4; MKK4; PRKMK4; SAPK ERK kinase 1; SAPK/ERK kinase 1; SEK1; SERK1], [MAP2K4; MAP2K4; JNKK; MEK4; MKK4; SEK1; SKK1; JNKK1; SERK1; MAPKK4; PRKMK4; SAPKK1; SAPKK-1; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1; MAP kinase kinase 4; MAPKK 4; MEK 4; SEK1; SAPK kinase 1; SAPKK-1; SAPKK1; JNKK] |
Gene, Accession # | [MAP2K4], Gene ID: 6416, NCBI: P45985.1, UniProt: P45985 |
Catalog # | MBS176890 |
Price | $280 |
Order / More Info | MEK4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |