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Antigenic Specificity | Opa1, |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | chicken, human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Eight transcript variants encoding different isoforms, resulting from alternative splicing of exon 4 and two novel exons named 4b and 5b, have been reported for this gene. |
Immunogen | Immunogen: A synthetic peptide made to an internal region within residues 500-600 of the human protein. |
Other Names | [OPA1 protein; Dynamin-like 120 kDa protein, mitochondrial; dynamin-like 120 kDa protein, mitochondrial; OPA1, mitochondrial dynamin like GTPase; Optic atrophy protein 1], [OPA1; OPA1; NPG; NTG; MGM1; BERHS; largeG; MTDPS14; KIAA0567] |
Gene, Accession # | [OPA1], Gene ID: 4976, NCBI: AAH58013.1 |
Catalog # | MBS555158 |
Price | $345 |
Order / More Info | Opa1, Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |