DDX19B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDDX19B
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: DDX19B antibody detects endogenous levels of total DDX19B. Function: ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins.Subunit Structure: Interacts with NUP214 or RNA in a mutually exclusive manner.Similarity: The N-terminal extension helix acts as an autoinhibitory domain, preventing ATP hydrolysis, unless the N-terminus of the protein is displaced by RNA binding, allowing cleft closure to bring key side chains into position for catalysis. Belongs to the DEAD box helicase family. DDX19/DBP5 subfamil
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cytoplasm. Nucleus > Nuclear Pore Complex. Nucleus Membrane. Nuclear pore complex cytoplasmic fibrils. Predicted Cross Reactivity: Pig, Bovine, Chicken Similarity: Pig (100%), Bovine (91%), Chicken (82%)
Other Names[ATP-dependent RNA helicase DDX19B; DBP5; Dbp5, yeast, homolog of; DD19B_HUMAN; DDX19; DDX19B; DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B; DEAD box protein 19B; DEAD box RNA helicase DEAD5; DEAD-box protein 5; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (Dbp5, yeast, homolog); DEAD/H BOX 19; helicase DEAD5; RNAh; TDBP; yeast Dbp5 homolog]
Gene, Accession #[DDX19B], Gene ID: 11269, NCBI: NP_001014449.1, UniProt: Q9UMR2
Catalog #MBS9605273
Price$240, $280
Order / More InfoDDX19B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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