Myelin Protein Zero Picoband Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMyelin Protein Zero Picoband
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionDescription: Myelin protein zero (P0, MPZ) is a glycoprotein which in humans is encoded by the MPZ gene. This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy
ImmunogenImmunogen: E Coli-derived human Myelin Protein Zero recombinant protein (Position: I30-R153). Subcellular Localization: Cell membrane; Single-pass type I membrane protein. Cell membrane. Tissue Specificity: Found only in peripheral nervous system Schwann cells.
Other Names[Myelin protein P0; Myelin peripheral protein; MPP; Myelin protein zero; MPZ]
Gene, Accession #[MPZ], Gene ID: 4359, NCBI: NP_000521.2, UniProt: P25189
Catalog #MBS1750537
Price$280
Order / More InfoMyelin Protein Zero Picoband Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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