Phospho-AKT1/2/3(Tyr315/316/312) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-AKT1/2/3(Tyr315/316/312) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunoflurescene (IF), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-AKT1/2/3(Tyr315/316/312) antibody detects endogenous levels of AKT1/2/3. Function: AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negat |
| Immunogen | Immunogen: A synthesized peptide derived from human AKT1/2/3 around the phosphorylation site of Tyr315/316/312. Subcellular Location: Cytoplasm. Nucleus. Cell Membrane. Nucleus after activation by integrin-linked protein kinase 1 (ILK1). Nuclear translocation is enhanced by interaction with TCL1A. Phosphorylation on Tyr-176 by TNK2 results in its localization to the cell membrane where it is targeted for further phosphorylations on Thr-308 and Ser-473 leading to its activation and the activated |
| Other Names | [AKT; AKT1; AKT1 kinase; AKT1m; AKT2; AKT2 kinase; Akt3; AKT3_HUMAN; CAKT; CWS6; DKFZp434N0250; HIHGHH; kinase Akt1; MGC99656; MPPH; Murine thymoma viral (v-akt) homolog 2; PKB ALPHA; PKB; PKB beta; PKB gamma; PKB-GAMMA; PKB/Akt; PKBALPHA; PKBB; PKBBETA; PKBG; PKBGAMMA; PRKBA; PRKBB; PRKBG; Protein kinase Akt 2; Protein kinase Akt-3; Protein kinase B alpha; Protein kinase B; Protein kinase B beta; Protein kinase B gamma; Proto oncogene c Akt; RAC ALPHA; RAC alpha serine/threonine protein kinase; RAC; RAC BETA; RAC beta serine/threonine protein kinase; RAC PK alpha; RAC PK beta; rac protein kinase alpha; rac protein kinase beta; RAC-gamma; RAC-gamma serine/threonine-protein kinase; RAC-PK-gamma; RACALPHA; RACalpha serine/threonine kinase; RACBETA; RACgamma; RACgamma serine/threonine protein kinase; RACPKgamma; serine threonine protein kinase; STK-2; STK2; thymoma viral proto oncogene 1; thymoma viral proto oncogene; V akt murine thymoma viral oncogene homolog 1; V akt murine thymoma viral oncogene homolog 2; V akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); V akt murine thymoma viral oncogene homolog 3; vakt murine thymoma viral oncogene homolog 1; vakt murine thymoma viral oncogene homolog 2; vakt murine thymoma viral oncogene homolog 3] |
| Gene, Accession # | [AKT1], Gene ID: 207, NCBI: NP_001014431.1, UniProt: P31749 |
| Catalog # | MBS9600617 |
| Price | $240, $280 |
| Order / More Info | Phospho-AKT1/2/3(Tyr315/316/312) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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