HLA Class I Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-HLA Class I antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | HLA Class I |
| Clone | [BRA-23/9] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.5 mL |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC-Frozen) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody BRA-23/9 is directed against a non-polymorphic determinant of human HLA Class I. The antibody has not been tested for cross reactivity with other species. The major histocompatibility complex (MHC) is a cluster of genes that play an important role in the immune response. In humans, this complex is referred to as the Human Leucocyte Antigen (HLA) system. There are three major HLA class I genes which are HLA-A, HLA-B and HLA-C. These are highly polymorphic and thousands of alleles are known to exist. The HLA-A, B and C gene products are heterodimeric cell surface glycoproteins which all consist of a 40-45kD MHC-encoded alpha chain and a non-covalently linked non-MHC encoded light chain (b2-microglobulin) of 12kDa. These proteins |
| Immunogen | Source Note: BRA-23/9 is a mouse monoclonal IgG2a antibody derived by fusion of mouse myeloma cells with cells from a mouse immunized with REH cells, a human pre-B cell leukaemia cell line. |
| Other Names | [HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, A-1 alpha chain; antigen presenting molecule; leukocyte antigen class I-A; MHC class I antigen HLA-A heavy chain; major histocompatibility complex, class I, A; MHC class I antigen A*1], [HLA-A; HLA-A; HLAA; HLAA] |
| Gene, Accession # | [HLA], Gene ID: 3105, NCBI: NP_001229687.1, UniProt: P30443 |
| Catalog # | MBS570324 |
| Price | $415 |
| Order / More Info | HLA Class I Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Tanaka J, Toubai T, Tsutsumi Y, Miura Y, Kato N, Umehara S, Kahata K, Mori A, Toyoshima N, Ota S, Kobayashi T, Kobayashi M, Kasai M, Asaka M, Imamura M. (2004). Cytolytic activity and regulatory functions of inhibitory NK cell receptor-expressing T cells expanded from granulocyte colony-stimulating factor-mobilized peripheral blood mononuclear cells. Blood 104:768-74.2. Toth J, Kubes M. (1993). Masking of HLA class I molecules expressed on K-562 target cells can restore their susceptibility to NK cell cytolysis. Immunobiology. 188:134-44. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies