Caspase-1(P10) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase-1(P10)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionDescription: Rabbit IgG polyclonal antibody for Caspase-1(CASP1) detection. Tested with WB, IHC-P in Human. Background: Caspase 1, apoptosis-related cysteine protease, is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta, IL18, and IL33 precursor proteins. Caspase 1 was purified ICE from the cytosol of the THP. human monocytic cell line and found that the active protease was made up of 2 peptides, which they called p20 and p10 based on their apparent molecular masses by SDS-PAGE. It belongs to a family of cysteine proteases known as caspases that always cleave proteins following an aspartic acid residue. The Caspase1 gene consists of 10 exons spanning at least 10.6
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Caspase-1 (P10) (249-262aa VFIGRLIEHMQEYA).
Other Names[Caspase-1(CASP-1); caspase 1, apoptosis-related cysteine peptidase; CASP 1; CASP-1; CASP1; CASP1_HUMAN; Caspase 1 apoptosis related cysteine peptidase; Caspase 1 apoptosis related cysteine protease; Caspase-1 subunit p10; Caspase1; ICE; IL 1 beta converting enzyme; IL 1BC; IL-1 beta-converting enzyme; IL-1BC; IL1 beta converting enzyme; IL1B convertase; IL1BC; IL1BCE; Interleukin 1 beta convertase; Interleukin 1 beta convertase precursor; Interleukin 1 beta converting enzyme; Interleukin 1B converting enzyme; Interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; P45], [CASP1; CASP1; ICE; P45; IL1BC; IL1BC; IL1BCE; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme]
Gene, Accession #[CASP1], Gene ID: 834, NCBI: P29466.1, UniProt: P29466
Catalog #MBS175294
Price$315
Order / More InfoCaspase-1(P10) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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