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Antigenic Specificity | LILRB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.7 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total LILRB2 protein. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and li |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
Other Names | [ILT4; LIR2; CD85D; LIR-2; MIR10; LILRA6; MIR-10] |
Gene, Accession # | [LILRB2], Gene ID: 10288, NCBI: Q8N423.4, UniProt: Q8N423 |
Catalog # | MBS9405851 |
Price | $255 |
Order / More Info | LILRB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |