Phospho-MAP2K3-S189 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-MAP2K3-S189
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionMKK3 and MKK6 are two closely related dual-specificity protein kinases that activate p38 MAP kinase (1-5). MKK3 and MKK6 both phosphorylate and activate p38 MAP kinase at its activation site, Thr-Gly-Tyr, but do not phosphorylate or activate Erk1/2 or SAPK/JNK. Phosphorylation of p38 MAP kinase dramatically stimulates its ability to phosphorylate protein substrates such as ATF-2 and Elk-1. MKK3 and MKK6 are both activated by different forms of cellular stress and inflammatory cytokines (4,5). Activation of MKK3 and MKK6 occurs through phosphorylation of Ser189 and Thr193 on MKK3 (2) and Ser207 and Thr211 on MKK6 (4,5).
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding S189 of human MAP2K3
Other Names[Phospho-MAP2K3-S189: MEK3; MKK3; MAPKK3; PRKMK3; SAPKK2; SAPKK-2], [MAP2K3; MAP2K3; MEK3; MKK3; MAPKK3; PRKMK3; SAPKK2; SAPKK-2; MEK3; MKK3; PRKMK3; SKK2; MAP kinase kinase 3; MAPKK 3; MEK 3; SAPK kinase 2; SAPKK-2; SAPKK2]
Gene, Accession #[MAP2K3], Gene ID: 5606, NCBI: P46734.2, UniProt: P46734
Catalog #MBS125716
Price$235, $350, $525
Order / More InfoPhospho-MAP2K3-S189 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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