SIRT1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | SIRT1 |
| Clone | [1089CT5.3.1] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG3,k |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is generated from a mice immunized with a recombinant protein between 1-180 amino acids from human. NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively. Serves as a sensor of the cytosolic ratio of NAD(+)/NADH |
| Immunogen | n/a |
| Other Names | [NAD-dependent protein deacetylase sirtuin-1; hSIRT1; 351-; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2; SirtT1 75 kDa fragment; 75SirT1; SIRT1; SIR2L1] |
| Gene, Accession # | [SIRT1], Gene ID: 23411, NCBI: NP_001135970.1, UniProt: Q96EB6 |
| Catalog # | MBS9200483 |
| Price | $165, $370 |
| Order / More Info | SIRT1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Frye R.A.,et al.Biochem. Biophys. Res. Commun. 260:273-279(1999). Takata T.,et al.Biochem. Biophys. Res. Commun. 301:250-257(2003). Deloukas P.,et al.Nature 429:375-381(2004). Vaziri H.,et al.Cell 107:149-159(2001). Langley E.,et al.EMBO J. 21:2383-2396(2002). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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