FASN Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFASN
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionFatty acid synthase (FASN) catalyzes the synthesis of long-chain fatty acids from acetyl-CoA and malonyl-CoA. FASN is active as a homodimer with seven different catalytic activities and produces lipids in the liver for export to metabolically active tissues or storage in adipose tissue. In most other human tissues, FASN is minimally expressed since they rely on circulating fatty acids for new structural lipid synthesis (1).Recently, increased expression of FASN has emerged as a phenotype common to most human carcinomas. In breast cancer, immunohistochemical staining showed that the levels of FASN are directly related to the size of breast tumors (2). Studies also showed that FASN is highly expressed in lung and prostate cancers and that FAS
ImmunogenImmunogen: Recombinant protein of human FASN Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[FASN; FAS; MGC14367; MGC15706; OA-519; SDR27X1]
Gene, Accession #[FASN], Gene ID: 2194, NCBI: NP_004095.4, UniProt: P49327
Catalog #MBS8500690
Price$310
Order / More InfoFASN Antibody from MYBIOSOURCE INC.
Product Specific References1. Katsurada, A. et al. (1990) Eur J Biochem 190, 427-33. 2. Wells, W.A. et al. (2006) Breast Cancer Res Treat 98, 231-40. 3. Kawamura, T. et al. (2005) Pathobiology 72, 233-240. 4. Shah, U.S. et al. (2006) Hum Pathol 37, 401-409. 5. Kuhajda, F.P. (2000) Nutrition 16, 202-8. 6. Tian, W.X. (2006) Curr Med Chem 13, 967-977. 7. Kusunoki, J. et al. (2006) Endocrine 29, 91-100.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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