FOXP3/Scurfin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFOXP3/Scurfin
Clonepolyclonal
Host SpeciesGoat
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Western Blot (WB), ELISA (EIA)
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DescriptionFOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, i
ImmunogenImmunogen: Synthetic peptide: SQRPSRCSNPTPGP, from the C Terminus of the protein sequence according to NP_054728.2; NP_001107849.1.
Other Names[forkhead box protein P3 isoform b; Forkhead box protein P3; forkhead box protein P3; forkhead box P3; Scurfin], [FOXP3; FOXP3; JM2; AIID; IPEX; PIDX; XPID; DIETER; IPEX]
Gene, Accession #[FOXP3], Gene ID: 50943, NCBI: NP_001107849.1, UniProt: Q9BZS1
Catalog #MBS555906
Price$425
Order / More InfoFOXP3/Scurfin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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