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Antigenic Specificity | CD3-epsilon |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD3-epsilon Polyclonal Antibody detects endogenous levels of CD3-epsilon protein. CD3e molecule encoded by CD3E is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human CD3-epsilon |
Other Names | [Rabbit CD3-epsilon; CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e] |
Gene, Accession # | [CD3-epsilon], Gene ID: 916, NCBI: P07766.2, UniProt: P07766 |
Catalog # | MBS9703842 |
Price | $130, $220, $325 |
Order / More Info | CD3-epsilon Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |