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Antigenic Specificity | PDGFRB (Tyr751) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PDGFRB antibody (Tyr751) detects endogenous levels of PDGFR beta only when phosphorylated at tyrosine 751. PDGFRB binds members of the platelet-derived growth factor family. The identity of the growth factor bound determines whether the functional receptor is a homodimer or a heterodimer, composed of both PDGFR-alpha and -beta. Ligand binding induces receptor dimerization and autophosphorylation, thereby recruiting SH2-containing proteins including Grb2, Src, GAP, PTPN11, PI3 kinase, PLC-gamma and Nck. |
Immunogen | Immunogen: PDGFRB antibody was raised in Rabbit using a synthesized phosphopeptide derived from human PDGFR beta around the phosphorylation site of tyrosine 751 (V-D-YP-V-P) as the immunogen. |
Other Names | [Rabbit PDGFRB (Tyr751); PDGFRB; PDGFRB; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140B; JTK12; PDGF-R-beta; PDGFR; PDGFR1; PDGFRB; PGFRB; platelet-derived growth factor receptor beta polypeptide] |
Gene, Accession # | [PDGFRB], Gene ID: 5159, UniProt: P09619 |
Catalog # | MBS5313761 |
Price | $375 |
Order / More Info | PDGFRB (Tyr751) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |