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Antigenic Specificity | CD39, Ectonucleoside triphosphate diphosphohydrolase 1 |
Clone | [R22] |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody R22 is directed against human CD39. The antibody has not been tested for cross reactivity with other species. CD39 is a transmembrane cell surface protein, which is a member of the ecto-nucleoside triphosphate diphosphohydrolase (ENTPDase) family. The CD39 molecule is primarily involved in the metabolism of purine nucleotides, converting extracellular adenosine triphosphate (ATP) and adenosine diphosphate (ADP) to adenosine monophosphate (AMP). In conjunction with CD73 (5' nucleotidase), CD39 plays a key role in regulating immunity and inflammation through the production of adenosine and purinergic signalling pathways. In addition, CD39 is reported to mediate B cell homotypic adhesion and inhibit ADP-induced platelet aggregatio |
Immunogen | Product Type: Primary Antibodies. Source Note: R22 is a rat monoclonal IgG1 antibody derived by fusion of SP2/0 mouse myeloma cells with splenocytes from a WAG/Rij rat immunized with JY cells, a human B lymphoblastoid cell line. |
Other Names | [ectonucleoside triphosphate diphosphohydrolase 1 isoform 2; Ectonucleoside triphosphate diphosphohydrolase 1; ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; CD39 antigen; ecto-apyrase; ecto-ATPase 1; ecto-ATPDase 1; ecto-ATP diphosphohydrolase 1; lymphoid cell activation antigen; ectonucleoside triphosphate diphosphohydrolase 1; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD_antigen: CD39], [ENTPD1; ENTPD1; CD39; SPG64; ATPDase; NTPDase-1; CD39; NTPDase 1; Ecto-ATPDase 1; Ecto-ATPase 1] |
Gene, Accession # | [CD39], Gene ID: 953, NCBI: NP_001091645.1, UniProt: P49961 |
Catalog # | MBS570338 |
Price | $415 |
Order / More Info | CD39, Ectonucleoside triphosphate diphosphohydrolase 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Kansas GS, Wood GS, Tedder TF. (1991). Expression, distribution and biochemistry of CD39. J Immunol. 146:2235-2244. |