HDAC3 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | HDAC3 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 'Lys- 27' (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activity and repressing proximal gene expression. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 |
| Immunogen | Immunogen: A synthesized peptide derived from human HDAC3. Subcellular Localization: Nucleus. Cytoplasm. Cytoplasm, cytosol. Colocalizes with XBP1 and AKT1 in the cytoplasm (PubMed: 25190803). Predominantly expressed in the nucleus in the presence of CCAR2. Tissue Specificity: Widely expressed. |
| Other Names | [Histone deacetylase 3; HD3; 3.5.1.98; RPD3-2; SMAP45; HDAC3], [HDAC3; HDAC3; HD3; RPD3; RPD3-2; HD3] |
| Gene, Accession # | [HDAC3], Gene ID: 8841, NCBI: NP_003874.2, UniProt: O15379 |
| Catalog # | MBS179471 |
| Price | $160, $340, $340 |
| Order / More Info | HDAC3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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