Puma BH3 Domain, 119-154 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Puma BH3 Domain, 119-154 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, rat) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Puma BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-154 amino acids from human Puma BH3 Domain. PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis. |
| Immunogen | n/a |
| Other Names | [Bcl-2-binding component 3; JFY-1; p53 up-regulated modulator of apoptosis; BBC3; PUMA] |
| Gene, Accession # | [BBC3], Gene ID: 27113, NCBI: NP_001120712.1, UniProt: Q9BXH1 |
| Catalog # | MBS9207882 |
| Price | $165, $370 |
| Order / More Info | Puma BH3 Domain, 119-154 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Liu, F.T., et al., Biochem. Biophys. Res. Commun. 310(3):956-962 (2003). Hoque, M.O., et al., Cancer Lett. 199(1):75-81 (2003). Yu, J., et al., Proc. Natl. Acad. Sci. U.S.A. 100(4):1931-1936 (2003). Han, J., et al., Proc. Natl. Acad. Sci. U.S.A. 98(20):11318-11323 (2001). Nakano, K., et al., Mol. Cell 7(3):683-694 (2001). |
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MYBIOSOURCE INC.
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