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Antigenic Specificity | Human DR3 (ED) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | Immunohistology Frozen, Western Blot (WB)* |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human DR3 recognizes death receptor 3. DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas/CD95 (Chinnaiyan, A. et al. 1996). The receptor for DR3 has very recently been identified and has been termed Apo-3L (Marsters, S. et al. 1998). DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, a functionally induces apoptosis and NF-KB activation. |
Immunogen | Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to DR3 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography. Target Species: Human |
Other Names | [tumor necrosis factor receptor superfamily member 25 isoform 12; Tumor necrosis factor receptor superfamily member 25; tumor necrosis factor receptor superfamily member 25; apoptosis inducing receptor; apoptosis-inducing receptor AIR; apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; death domain receptor 3 soluble form; death receptor beta; lymphocyte-associated receptor of death; protein WSL-1; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein); tumor necrosis factor receptor superfamily, member 25; Apo-3; Apoptosis-inducing receptor AIR; Apoptosis-mediating receptor DR3; Apoptosis-mediating receptor TRAMP; Death receptor 3; Lymphocyte-associated receptor of death; LARD; Protein WSL; Protein WSL-1], [TNFRSF25; TNFRSF25; DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; WSL-LR; TNFRSF12; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; LARD] |
Gene, Accession # | [DR3], Gene ID: 8718, NCBI: NP_001034753.1, UniProt: Q93038 |
Catalog # | MBS221576 |
Price | $375 |
Order / More Info | Human DR3 (ED) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |