Edit |   |
---|---|
Antigenic Specificity | Human HTRA2 |
Clone | [P1B3AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: HtrA2 also called Omi is a mammalian serine protease at high temperatures and has a chaperone activity at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain; an inhibitor of apoptosis protein (IAP)-binding motif; a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death. |
Immunogen | Immunogen: Anti-human HTRA2 mAb is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HTRA2 amino acids 134-458 purified from E Coli. |
Other Names | [HTRA2; HTRA2, Mouse Human; Serine protease HTRA2 mitochondrial; EC 3.4.21.108; High temperature requirement protein A2; HtrA2; Omi stress-regulated endoprotease; Serine proteinase OMI; Serine protease 25; OMI; PARK13; PRSS25], [HtrA2; HtrA2; CG8464; DmelCG8464; DmHtrA2; domi; dOmi; htrA2; htrA2/omi; HtrA2/Omi; omi; Omi] |
Gene, Accession # | [HTRA2], Gene ID: 41756, NCBI: NP_001262565.1 |
Catalog # | MBS140197 |
Price | $140, $205, $505 |
Order / More Info | Human HTRA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |