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Antigenic Specificity | CISH |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [CIS; G18; SOCS; CIS-1; BACTS2] |
Gene, Accession # | [CISH], Gene ID: 1154, NCBI: Q9NSE2.1, UniProt: Q9NSE2 |
Catalog # | MBS9127696 |
Price | $200, $275, $430 |
Order / More Info | CISH Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |