ITGAM Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityITGAM
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration0.8 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total ITGAM protein. This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human integrin, alpha M (complement component 3 receptor 3 subunit)
Other Names[CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6]
Gene, Accession #[ITGAM], Gene ID: 3684, NCBI: NP_000623.2, UniProt: P11215
Catalog #MBS9409256
Price$255
Order / More InfoITGAM Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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