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Antigenic Specificity | ITGAM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.8 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ITGAM protein. This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human integrin, alpha M (complement component 3 receptor 3 subunit) |
Other Names | [CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6] |
Gene, Accession # | [ITGAM], Gene ID: 3684, NCBI: NP_000623.2, UniProt: P11215 |
Catalog # | MBS9409256 |
Price | $255 |
Order / More Info | ITGAM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |