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Antigenic Specificity | SNX17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)). |
Immunogen | Immunogen: Recombinant Human Sorting nexin-17 protein (280-457AA) |
Other Names | [Sorting nexin-17; SNX17; KIAA0064] |
Gene, Accession # | [SNX17], Gene ID: 9784, NCBI: NP_001253989.1, UniProt: Q15036 |
Catalog # | MBS7050123 |
Price | $160, $235 |
Order / More Info | SNX17 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |