casp8 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-casp8 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | casp8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Apoptosis induced through the CD95 receptor (Fas/APO-1) and tumor necrosis factor receptor 1 (TNFR1) activates caspase-8 and leads to the release of the caspase-8 active fragments, p18 and p10 (1-3). Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1, -3, -6, and -7. Caspase-3 ultimately elicits the morphological hallmarks of apoptosis, including DNA fragmentation and cell shrinkage. |
| Immunogen | Immunogen: A synthetic peptide of human casp8 |
| Other Names | [Casp8 Rabbit pab], [casp8; Apoptotic protease Mch 5; Caspase8; CAP4; FLICE; Apoptotic cysteine protease] |
| Gene, Accession # | Gene ID: 841, NCBI: NP_001073593.1, UniProt: Q14790 |
| Catalog # | MBS125310 |
| Price | $200, $275, $430 |
| Order / More Info | casp8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Muzio, M. et al. (1996) Cell 85, 817-827. 2. Boldin, M.P. et al. (1996) Cell 85, 803-815. 3. Fernandes-Alnemri, T. et al. (1996) Proc. Natl. Acad. Sci. USA 93, 7464-7469 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies