RPS6KB1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRPS6KB1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
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DescriptionThe antibody detects endogenous level of total RPS6KB1 protein. p70 S6 kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression (1,2). p70 S6 kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5' oligopyrimidine tract mRNAs (1). A second isoform, p85 S6 kinase, is derived from the same gene and is identical to p70 S6 kinase except for 23 extra residues at the amino terminus, which encode a nuclear localizing signal (1). Both isoforms lie on a mitogen activated signaling pathway downstream of phosphoinositide-3 kinase (PI-3K) and the target of rapamycin, FRAP/mTOR, a pathway distinct from the Ras/MAP kinase cascade (1). The a
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human RPS6KB1.
Other Names[PS6K; S6K; S6K1; STK14A; p70(S6K)-alpha]
Gene, Accession #[RPS6KB1], Gene ID: 6198, NCBI: NP_001258971.1, UniProt: P23443
Catalog #MBS9414782
Price$255
Order / More InfoRPS6KB1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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