CREST Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCREST
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1mg/mL
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionSS18-like 1 (SS18L1) is a transcriptional activator that is required for calcium-dependent dendritic growth and branching in cortical neurons. It's also a nuclear protein interacts with CREB-binding protein and expressed in the developing brain. It helps regulate neuronal morphogenesis in calcuim-dependent manner. The N-terminal domain of SS18L1 is required for suppressing transactivation in the basal state, while the C-terminal domain is required for calcium-induced transactivation. It's part of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. This complex also binds to the NR2B promoter, and activ
ImmunogenImmunogen: CREST fusion protein ag3119
Other Names[CREST; KIAA0693; LP2261; SS18 like protein 1; SS18L1; SYT homolog 1]
Gene, Accession #[CREST], Gene ID: 26039, NCBI: NP_001288707.1, UniProt: O75177
Catalog #MBS2540181
Price$220, $290, $435
Order / More InfoCREST Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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