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Antigenic Specificity | KCNQ2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. |
Immunogen | Immunogen: Recombinant protein of human KCNQ2 |
Other Names | [BFNC; EBN; EBN1; ENB1; HNSPC; KCNA11; KV7.2] |
Gene, Accession # | [KCNQ2], Gene ID: 3785, NCBI: O43526.2, UniProt: O43526 |
Catalog # | MBS9132757 |
Price | $200, $275, $430 |
Order / More Info | KCNQ2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |