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Antigenic Specificity | MEK-3 (Phospho Ser218) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-MEK-3 (S189) Polyclonal Antibody detects endogenous levels of MEK-3 protein only when phosphorylated at S189. Mitogen-activated protein kinase 3 encoded by MAP2K3 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. Mitogen-activated protein kinase 3 is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. Mitogen-activated protein kinase 3 can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAP |
Immunogen | Immunogen: Synthesized peptide derived from human MEK-3 around the phosphorylation site of S189 |
Other Names | [Rabbit MEK-3 (phospho Ser218); MAP2K3; MEK3; MKK3; PRKMK3; SKK2; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPKK 3; MAPK/ERK kinase 3; MEK 3; Stress-activated protein kinase kinase 2; SAPK kinase 2; SAPKK-2; SAPKK2] |
Gene, Accession # | [MEK-3], Gene ID: 5606, NCBI: NP_002747.2, UniProt: P46734 |
Catalog # | MBS9701110 |
Price | $130, $220, $325 |
Order / More Info | MEK-3 (Phospho Ser218) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |