Human CD152 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human CD152 antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | Human CD152 |
| Clone | [4AA36B10] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG2a |
| Format | phycoerythrin (PE) conjugate |
| Size | 50 tests, 100 tests |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The 4AA36B10 monoclonal antibody reacts with human CD152, also known as cytotoxic T lymphocyte antigen-4 (CTLA-4). CTLA-4, a protein with structural similarities to CD28, is expressed on activated T cells (activated B cells may also express CTLA-4) and binds the B7 family members, CD80 (B7-1) and CD86 (B7-2), with higher affinity than CD28 does. CTLA-4 and CD28 appear to deliver opposing signals to T cells: while CD28 is a potent costimulator, CTLA-4 restricts the progression of T cells to an activated state by inhibiting IL-2 secretion and cellular proliferation. The cytoplasmic portion of CTLA-4 contains ER retention motifs, resulting in intracellular localization of a large proportion of newly synthesized CTLA-4 in response to TCR signal |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | [CD152] |
| Catalog # | MBS8501809 |
| Price | $280, $300 |
| Order / More Info | Human CD152 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Vandenborre K, et al. American Journal of Pathology (1998) 152: 963-73. 2. Vandenborre K, et al. Immunology (1999) 98: 1-10. 3. T.L. Walunas, et al. Immunity (1994) 1: 405-413. 4. N.J. Karandikar, et al. Journal of Experimental Medicine (1996) 184: 783-788. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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