SOX2 (C-term) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SOX2 (C-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted reactivity: chicken) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SOX2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 282-316 amino acids from the C-terminal region of human SOX2. Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). |
| Immunogen | n/a |
| Other Names | [Transcription factor SOX-2; SOX2] |
| Gene, Accession # | [SOX2], Gene ID: 6657, NCBI: NP_003097.1, UniProt: P48431 |
| Catalog # | MBS9205883 |
| Price | $165, $370 |
| Order / More Info | SOX2 (C-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Stevanovic M.,et al.Mamm. Genome 5:640-642(1994). Sadler L.A.,et al.Submitted (DEC-1992) to the EMBL/GenBank/DDBJ databases. Fantes J.,et al.Nat. Genet. 33:461-463(2003). Takahashi K.,et al.Cell 131:861-872(2007). Rigbolt K.T.,et al.Sci. Signal. 4:RS3-RS3(2011). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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