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Antigenic Specificity | Histone H2A.X (Phospho-Ser139) |
Clone | [8H4-1H11-F8] |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 4.26mg/ml |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. |
Immunogen | Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Ser139 of human H2A.X. Sensitivity: This antibody detects endogenous levels of H2A.X only when phosphorylated at serine 139. Sequence Similarities: Belongs to the histone H2A family. |
Other Names | [H2A histone family, member X; H2A.X; H2a/x; H2AFX; H2AX; H2AX histone; H2AX_HUMAN; Histone H2A.X; Histone H2AX], [H2AX; H2A.X; H2A/X] |
Gene, Accession # | [h2ax], Gene ID: 3014, NCBI: NP_002096.1, UniProt: P16104 |
Catalog # | MBS475213 |
Price | $335 |
Order / More Info | Histone H2A.X (Phospho-Ser139) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |