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Antigenic Specificity | ZC3H8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ZC3H8 antibody detects endogenous levels of total ZC3H8. Function: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.Subunit Structure: Component of the little elongation complex (LEC), at least composed of ELL (ELL, ELL2 or ELL3), ZC3H8, ICE1 and ICE2 |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus Predicted Cross Reactivity: Pig, Dog Similarity: Pig (85%), Dog (92%) |
Other Names | [Fliz1; Zc3h8; ZC3H8_HUMAN; Zinc finger CCCH domain containing protein 8; Zinc finger CCCH domain-containing protein 8] |
Gene, Accession # | [ZC3H8], Gene ID: 84524, NCBI: NP_115883.2, UniProt: Q8N5P1 |
Catalog # | MBS9606078 |
Price | $240, $280 |
Order / More Info | ZC3H8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |