APH1A (N-term), 41-70 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | APH1A (N-term), 41-70 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This APH1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human APH1A. APH1 is a multipass transmembrane protein that interactswith presenilin (see PSEN1; MIM 104311) and nicastrin (APH2; MIM605254) as a functional component of the gamma-secretase complex.The gamma-secretase complex is required for the intramembraneproteolysis of a number of membrane proteins, including theamyloid-beta precursor protein (APP; MIM 104760) and Notch (MIM190198). |
| Immunogen | n/a |
| Other Names | [Gamma-secretase subunit APH-1A; APH-1a; Aph-1alpha; Presenilin-stabilization factor; APH1A; PSF] |
| Gene, Accession # | [APH1A], Gene ID: 51107, NCBI: NP_001071096.1, UniProt: Q96BI3 |
| Catalog # | MBS9200854 |
| Price | $165, $370 |
| Order / More Info | APH1A (N-term), 41-70 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Mitsuishi, Y., et al. J. Biol. Chem. 285(20):14920-14931(2010) Chen, A.C., et al. J. Biol. Chem. 285(15):11378-11391(2010) Pardossi-Piquard, R., et al. J. Biol. Chem. 284(24):16298-16307(2009) Wang, Y., et al. Neurosci. Lett. 455(2):101-104(2009) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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