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Antigenic Specificity | IPR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IPR1 Antibody: Susceptibility to tuberculosis (TB) in mice has recently been attributed to the IPR1 gene. IPR1 is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. SP110 is the closest homolog of the IPR1 protein in humans. The IPR1/Sp110 gene product might play a role in integrating signals generated by intracellular pathogens with mechanisms controlling innate immunity, cell death, and pathogenesis. IPR1/Sp110 is up-regulat |
Immunogen | Immunogen: IPR1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of the human IPR1. Buffer: IPR1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [IPR1; IPR1; VODI; IFI41; IFI75; Sp110 nuclear body protein; Speckled 110 kDa; SP110 nuclear body protein], [SP110; SP110; IPR1; VODI; IFI41; IFI75] |
Gene, Accession # | [SP110], Gene ID: 3431, NCBI: NP_004501, UniProt: Q9HB58 |
Catalog # | MBS150343 |
Price | $375 |
Order / More Info | IPR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |