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Antigenic Specificity | WAVE1 (N-terminal region) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody was affinity purified using WAVE1 (Nterminal region) peptide (without carrier). The antibody detects an 80 kDa* protein corresponding to the molecular mass of WAVE1 on SDS-PAGE immunoblots of human SYF cSrc-transformed, HUVEC, and K562 cells, as well as rat PC12 cells and mouse C2C12 cells. The Wiskott-Aldrich syndrome protein (WASP) family is involved in various pathways that regulate actin cytoskeletal organization. This family includes WASP, N-WASP, and three WAVE/SCAR isoforms, WAVE1, 2, and 3. WAVE proteins play key roles in actin-mediated cell events, such as membrane ruffling and lamellipodia formation. WAVEs contain an Nterminal WAVE homology domain, a basic domain, a Proline-rich region, and carboxy terminal verprolin |
Immunogen | Immunogen: A synthetic peptide (coupled to KLH) corresponding to amino acid residues in the N-terminal half of human WAVE1. This sequence has highhomology with similar regions in rat and mouse WAVE1, and has less than 50% homology to similar regions in human WAVE2 and WAVE3. |
Other Names | [Wiskott-Aldrich syndrome verproline-homologous protein 1; Scar1; WASF1], [WASF1; WASF1; WAVE; SCAR1; WAVE1; FLJ31482; KIAA0269; KIAA0269; SCAR1; WAVE1] |
Gene, Accession # | Gene ID: 8936, NCBI: NP_001020107.1, UniProt: Q92558 |
Catalog # | MBS472069 |
Price | $385 |
Order / More Info | WAVE1 (N-terminal region) Antibody from MYBIOSOURCE INC. |
Product Specific References | • Ardern, H. et al. (2006) Cell Motil. Cytosk. 63:6.• Leng, Y. et al. (2005) PNAS 102(4):1098.• Suetsugu, S. et al. (1999) Bioch. Biophs. Res. Comm. 260:296.• Miki, H. et al. (1999) J Biol. Chem. 274(39):27605. |