CD163 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD163
Clonemonoclonal
Host Speciesn/a
Reactive Specieshuman
IsotypeIgG
Formataffinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionAcute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of I
ImmunogenImmunogen: A synthesized peptide
Other Names[Scavenger receptor cysteine-rich type 1 protein M130; Hemoglobin scavenger receptor; CD163; Soluble CD163; sCD163; CD163; M130; Scavenger receptor cysteine-rich type 1 protein M130]
Gene, Accession #[CD163], Gene ID: 9332, NCBI: NP_004235.4, UniProt: Q86VB7
Catalog #MBS7110797
Price$185, $265
Order / More InfoCD163 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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