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Antigenic Specificity | CD163 |
Clone | monoclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | IgG |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of I |
Immunogen | Immunogen: A synthesized peptide |
Other Names | [Scavenger receptor cysteine-rich type 1 protein M130; Hemoglobin scavenger receptor; CD163; Soluble CD163; sCD163; CD163; M130; Scavenger receptor cysteine-rich type 1 protein M130] |
Gene, Accession # | [CD163], Gene ID: 9332, NCBI: NP_004235.4, UniProt: Q86VB7 |
Catalog # | MBS7110797 |
Price | $185, $265 |
Order / More Info | CD163 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |