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Antigenic Specificity | PRKCA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Activation of protein kinase C (PKC) is one of the earliest events in a cascade that controls a variety of cellular responses, including secretion, gene expression, proliferation, and muscle contraction (1,2). PKC isoforms belong to three groups based on calcium dependency and activators. Classical PKCs are calcium-dependent via their C2 domains and are activated by phosphatidylserine (PS), diacylglycerol (DAG), and phorbol esters (TPA, PMA) through their cysteine-rich C1 domains. Both novel and atypical PKCs are calcium-independent, but only novel PKCs are activated by PS, DAG, and phorbol esters (3-5). Members of these three PKC groups contain a pseudo-substrate or autoinhibitory domain that binds to substrate-binding sites in the catalyt |
Immunogen | Immunogen: C term -peptide of human PRKCA Calculated Molecular Weight: 77kDa |
Other Names | [PKCalpha: PKCA; AAG6; PKCA; PRKACA; PKC-alpha; MGC129900; MGC129901; PRKCA], [PRKCA; PRKCA; AAG6; PKCA; PRKACA; PKC-alpha; PKCA; PRKACA; PKC-A; PKC-alpha] |
Gene, Accession # | [PRKCA], Gene ID: 5578, NCBI: P17252.4, UniProt: P17252 |
Catalog # | MBS125088 |
Price | $200, $275, $430 |
Order / More Info | PRKCA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |