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Antigenic Specificity | MCP-8 (Mast Cell Protease 8, Mcpt8) |
Clone | monoclonal |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | affinity purified |
Size | 0.025 mg, 0.1 mg |
Concentration | 0.5mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes mouse Mast Cell Protease 8. mMCP-8 and its rat homologues, rMCP-8, -9, and -10, form a new group of mast cell/basophil proteases, which are more closely related to the T-cell granzymes and neutrophil cathepsin G than to the mast cell tryptases and chymases. mMCP-8 showed a high degree of homology with mouse granzyme B in the critical regions for determining substrate cleavage specificity. It preferentially cleaves after Asp residues. mMCP-8 mRNA is highly expressed in a mouse connective tissue MC-like tumor line. However, it could not be detected in mouse liver, intestine, lung or ears, indicating very low expression in normal tissues. A strong increase in mMCP-8 levels in the lungs can be detected in infected animals. |
Immunogen | Immunogen: Recombinant GST-mouse mMCP-8 fusion protein expressed in E.coli. |
Other Names | [-MCP-8 (Mast Cell Protease 8, Mcpt8)] |
Gene, Accession # | Gene ID: 29333, NCBI: NP_062063.1, UniProt: Q9Z0M4 |
Catalog # | MBS6010758 |
Price | $370, $520 |
Order / More Info | MCP-8 (Mast Cell Protease 8, Mcpt8) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |