MCP-8 (Mast Cell Protease 8, Mcpt8) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMCP-8 (Mast Cell Protease 8, Mcpt8)
Clonemonoclonal
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a
Formataffinity purified
Size0.025 mg, 0.1 mg
Concentration0.5mg/ml
ApplicationsWestern Blot (WB)
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DescriptionRecognizes mouse Mast Cell Protease 8. mMCP-8 and its rat homologues, rMCP-8, -9, and -10, form a new group of mast cell/basophil proteases, which are more closely related to the T-cell granzymes and neutrophil cathepsin G than to the mast cell tryptases and chymases. mMCP-8 showed a high degree of homology with mouse granzyme B in the critical regions for determining substrate cleavage specificity. It preferentially cleaves after Asp residues. mMCP-8 mRNA is highly expressed in a mouse connective tissue MC-like tumor line. However, it could not be detected in mouse liver, intestine, lung or ears, indicating very low expression in normal tissues. A strong increase in mMCP-8 levels in the lungs can be detected in infected animals.
ImmunogenImmunogen: Recombinant GST-mouse mMCP-8 fusion protein expressed in E.coli.
Other Names[-MCP-8 (Mast Cell Protease 8, Mcpt8)]
Gene, Accession #Gene ID: 29333, NCBI: NP_062063.1, UniProt: Q9Z0M4
Catalog #MBS6010758
Price$370, $520
Order / More InfoMCP-8 (Mast Cell Protease 8, Mcpt8) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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